Realizing the benefits of human genetics and genomics research for people everywhere.
The American Society of Human Genetics (ASHG) today published a new Guidance on the challenges in the development and application of polygenic scores (PGS) in human genetic research. Appearing in today’s issue of the American Journal of Human Genetics (AJHG), this new resource was developed by a writing group led by members of the ASHG... Read More
Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What prompted you to start working on this project? SR: When discussing the potential clinical utility of polygenic risk scores, a typical question from the audience is, “Why bother testing your genetic risk profile when the role of genetic risk can simply be measured using a... Read More
Posted By: HGG Advances What motivated you to start working on this project? Over billions of years of evolution since their endosymbiotic origin, mitochondria have ceded the genetic code that controls most of their form and function to the nuclear genome. What was fascinating to me is that mitochondria retained a small circular genome (mtDNA)... Read More
For Immediate Release: Thursday, November 10, 2022, 10:00 a.m. U.S. Eastern Time Media Contact: Kara Flynn, (202) 257-8424, press@ashg.org ROCKVILLE, MD –The American Society of Human Genetics (ASHG) today released the Human Genetics & Genomics Workforce Survey Report, which takes an in-depth look at the field’s workforce demographics, including race, ethnicity, or ancestry; gender identity; sexual... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? JY: This project was motivated by my previous work about developing a Bayesian Functional GWAS (BFGWAS) method to account for non-overlapped categorical functional annotation for multivariate GWAS. Our previous work of the initial BFGWAS method has shown the advantages of accounting... Read More