AJHG

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? JT: The unresolved mystery of personal history. Alright, that’s unnecessarily cryptic, let me try again. Upon completing my undergraduate studies, I found myself the unwilling protagonist of a medical odyssey, one highlighted by indiscriminate immune attack and... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? LS: Since the Wise et al., AJHG 2013 eXclusion report ten years ago that documented that the X chromosome was typically excluded from GWAS, my lab has been thinking about developing statistical methods for the X chromosome,... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? RD: Revisionist circles in African anthropology were having important discussions about how we understand ethnicity of past groups in Southern Africa. One big take-home message was that some labels used in historic texts have been mistakenly taken... Read More

Posted By: Kylee Spencer, PhD, Assistant Editor, AJHG KS: What motivated you to start working on this project? SI: Ossification of the posterior longitudinal ligament of the spine (OPLL) is an intractable disease that causes spinal canal stenosis leading to myelopathy and/or radiculopathy. OPLL is a common disease. Its prevalence is more than 2% in... Read More

Inside AJHG: A Chat with Mitchell Machiela KS: What motivated you to start working on this project? MM: Our main motivation for this study was to better understand how germline genetic variation in the 6p25.1 Ewing sarcoma (EwS) susceptibility locus contributes to EwS risk. Specifically, based on evidence from a prior investigation of the 10q21.3... Read More