Paper Spotlight

Kritika Singh, BS, PhD Candidate Vanderbilt Genetic Institute, Vanderbilt University Medical Center Singh K, et al. Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization. 2021 Nature Communications 12, 4569. ASHG: Can you describe the type of research that has your primary focus? Kritika: My overarching research goals focus on understanding the shared biology of various... Read More

It is well known that both nature and nurture play a large role in our long-term health outcomes. However, the gene by environment dynamics for many complex traits is still poorly understood. Justyna Resztak and colleagues added to this growing body of literature through their study by understanding the genetic effects of psychosocial experiences on... Read More

Kelsey Dawes, BS, PhD Candidate Molecular Medicine, Department of Psychiatry, University of Iowa. Molecular Diagnostic Intern, Behavioral Diagnostics LLC Dawes K, et al. Refinement of cg05575921 demethylation response in nascent smoking. 2020 Clinical Epigenetics 12, 92. You may not be surprised to hear that if you ask a teenager if they smoke, their answer might... Read More

Anna Miller, BA Ph.D. Candidate in Genetics and Genome Sciences Case Western Reserve University Miller AK, et al. A novel mapping strategy utilizing mouse chromosome substitution strains identifies multiple epistatic interactions that regulate complex traits. 2020 G3: Genes, Genomes, Genetics 10.12: 4553-4563. Genetic variation interacts in numerous complicated ways to impact the expression of complex... Read More

Trainee Author: Theodore G. Drivas, MD, PhD Research Fellow, Children’s Hospital of Philadelphia Clinical Associate, The Perelman School of Medicine at the University of Pennsylvania (Photo courtesy of Theodore G. Drivas) Drivas TG, et al. Mendelian pathway analysis of laboratory traits reveals distinct roles for ciliary subcompartments in common disease pathogenesis. 2021 American Journal of... Read More