Posted By: HGG Advances HGGA: what motivated you to start working on this project MB: Being an early-stage investigator is challenging. You enter a new department with existing models of success and expectations of establishing an independent lab. However, having completed my graduate and post-graduate training in highly collaborative environments, e.g., working closely with analysis... Read More
Posted By: Alyson Barnes, PhD, Assistant Editor, AJHG AB: What motivated you to start working on this project? JH: One of my interests in genetics research is to help reduce disparities between populations, so that we can achieve more inclusive and effective risk prediction/healthcare. Although more focused on the methodological aspects, in this project we... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? MG: The pathogenesis of ankylosing spondylitis (AS) remains poorly understood. In other immune-mediated diseases, integrating genome-wide association studies with epigenomics and transcriptomics has successfully identified key pathogenic cell types, such as T cells in rheumatoid arthritis and B cells in systemic... Read More
Posted By: Alyson Barnes, PhD, Assistant Editor, AJHG AB: What motivated you to start working on this project? AH: Although I was born in Armenia, I emigrated at the age of three and spent most of my life living abroad. Over the years, I found myself feeling increasingly distanced from my homeland and its history.... Read More
Structural and genetic diversity in the secreted mucins MUC5AC and MUC5B Position: PhD Candidate, Department of Genome Sciences, University of Washington & Fred Hutch Cancer Center ASHG: Can you describe the type of research that has your primary focus? Elizabeth Plender: I study genetic variation in the mucins, a set of heterogenous loci that encode... Read More
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