Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? JD: As I began my PhD in statistical genetics, I wanted to start from the ground up. Much of the excitement in our field today centers on precision medicine, which utilizes genetics to refine disease risk prediction, identify novel... Read More
Posted By: HGG Advances HGGA: What motivated you to start working on this project? Most genomic research has focused on individuals of European ancestry and has commonly used imputation panels that contain more European haplotypes, leading to poorer accuracy in other ancestries. In addition, standard panels are largely disease-agnostic, whereas ours is built from Alzheimer’s... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? FR: I had previously developed the graph machine learning framework, Speos, which specializes in the prediction of core genes across several traits. The respective paper, however, primarily focused on benchmarking, validation, and prediction accuracy. Although it... Read More
The American Society of Human Genetics (ASHG) is deeply concerned by the Executive Order (EO) issued last week titled “Improving Oversight of Federal Grantmaking.” While ASHG supports efforts to ensure transparency, accountability, and scientific rigor in federally funded research, we are particularly troubled that the EO’s directives risk introducing political considerations into the grantmaking process.... Read More
Posted By: The American Journal of Human Genetics, AJHG AJHG: What motivated you to start working on this project? JT: This project emerged from an empirical problem we were facing in a separate analysis. In that analysis, we wanted to examine the pattern of genetic variation driven by unique ancestry in human populations in order... Read More